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Manufacturing

Oligonucleotide Synthesis Capabilities

  • Synthesis scales from 10 nmol to 4 mmol. 
  • Dedicated equipment and reagents. 
  • The widest range of modifications (>100) in the industry, including dyes, spacers, linkers, and unique amidites only available through EUROGENTEC. 
  • Development and production of customized modifications. 
  • Automated or manual mixing of different backbones for wobble synthesis, creating degenerate sites within an oligo sequence. 
  • Specific amidite mixes according to your requests. 
  • Large selection of chemistries such as LNA®, Phosphorothioate, RNA, 2’OMe RNA, customized mixtures of backbones and chimeric oligos. Please inquire for the availability of additional modifications.

Purification


Applications and regulations in molecular diagnostic assays call for oligonucleotides that are of exceptional purity. EUROGENTEC offers several preparative purification options to meet and exceed our customers’ high-quality requirements: 

  • Anion Exchange HPLC 
  • Reverse Phase HPLC
  • Dedicated HPLC columns as requested
  • Dedicated Purification zones as requested
  • Multiple purification steps
  • PAGE
  • Disposable solid phase cartridge
  • Ultrafiltration (large scale only)

Delivery Options



  • Customized mixtures of individual oligonucleotides
  • Conjugated oligonucleotides (HRP, AP, synthetic peptides, proteins)
  • Filling (lyophilized or in solution with customized buffers) and labeling according to customer needs
  • Filling in Class 10 000-type HEPA air filtered room
  • Customized packaging and labelling

 

 

For inquiries, please contact our Diagnostic Oligonucleotide Team:

Muriel Craynest, Ph.D.
Tel.: +32 4 372 74 37

Peter Haima, Ph.D.
Tel.: +32 4 372 76 35

diagnostic.oligo@eurogentec.com


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