Home > Products > Products for MasterCycler® ep real plex > Products for iCycler iQ®, iQ5, My iQ® > K > Cholesteryl
Back to previous page

Cholesteryl

Life Science Molecular Diagnostics GMP BioManufacturing
Cholesteryl Build & Order
Antisense oligonucleotides must cross the cell membrane for optimal activity. When incorporated into an oligonucleotide, lipophilic groups, such as cholesteryl phosphoramidite, may enhance the permeation of cell membranes for optimal activity.

Name Synthesis scale Recommended Purification* Required Purification* Reference EUR
5' TEG-Cholesteryl 40 nmol PAGE - MD-CN040-05004 57.00
5' TEG-Cholesteryl 200 nmol PAGE - MD-CN040-05020 88.00
5' TEG-Cholesteryl 1000 nmol PAGE - MD-CN040-05100 119.00
3' TEG-Cholesteryl 40 nmol PAGE - MD-CN040-03004 84.30
3' TEG-Cholesteryl 200 nmol PAGE - MD-CN040-03020 167.50
3' TEG-Cholesteryl 1000 nmol PAGE - MD-CN040-03100 251.50
Internal Cholesteryl (dR) 40 nmol PAGE - MD-CN040-DR004 212.00
Internal Cholesteryl (dR) 200 nmol PAGE - MD-CN040-DR020 235.00
Internal Cholesteryl (dR) 1000 nmol PAGE - MD-CN040-DR100 258.50
* More info on the Purifications page

Quality Control

   MALDI-TOF Mass Spectrometry

Delivery times

   2-14 bases: 5 Working days
                             15-39 bases: 5 Working days
                             40-80 bases: 7-8 Working days
                             > 80 bases: 10 Working days

Packaging

   Dried

Shipping conditions

   Room temperature

Storage conditions

   -20 °C to -70 °C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.
dR-Cholesteryl (deoxyribose-Cholesteryl) modification allows the synthesis of oligonucleotides containing successive molecules of Cholesteryl anywhere in the sequence or on either terminus. Each label is linked to the deoxyribose via a 6 carbon atoms spacer. Each dR-Cholesteryl can also be separated by a spacer.



Legal notices

   For Research Use only

Order Forms

Leaflets

Product citations


LEGENDRE D. et al., "Engineering a regulatable enzyme for homogeneous immunoassays", Nature Biotechnology, vol. 17, n° 1, p.67-72, 1 January 1999


MOMENI P. et al., "Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I", Nature Genetics, vol. 24, p. 71-74, 1 January 2000


PEREL Y. et al., "Galanin and galanin receptor expression in neuroblastic tumours: correlation with their differentiation status", British Journal of Cancer, vol. 86, n° 1, p. 117-122, 7 January 2002


OSTERMANN G. et al., "JAM-1 is a ligand of the 2 integrin LFA-1 involved in transendothelial migration of leukocytes", Nature Immunology, vol. 3, n° 2, p.151-158, 1 February 2002


GOMEZ D. et al., "Interaction of Telomestatin with the Telomeric Single-strand Overhang", Journal of Biological Chemistry, vol. 279, n° 40, p. 41487-41494, October 2004


RZEM et al., "A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria", PNAS, vol. 101, n° 48, 16849-16854, November 2004


SU T.-J. et al., "DNA bending by M.EcoKI methyltransferase is coupled to nucleotide flipping", Nucleic Acids Research, vol. 33, n° 10, 3235-3244, June 2005


VAN DER STEEGE G. et al., "Persistent failures in gene repair", Nature Biotechnology, n° 19, p. 305-306, April 2001


ISCHENKO A.A. et al., "Alternative nucleotide incision repair pathway for oxidative DNA damage", Nature, n° 415, p. 183-187, 10 January 2002


KRISTENSEN A. et al., "Detection of Mutations in Exon 8 of TP53 by Temperature Gradient 96-Capillary Array Electrophoresis", Biotechniques, n° 33, p. 650-653, September 2002


VANDEN ABEELE F. et al., "Store-operated Ca2+ Current in Prostate Cancer Epithelial Cells", Journal of Biological Chemistry, vol. 278, n° 17, p. 15381-15389, April 2003


GROS L. et al., "Hijacking of the Human Alkyl-N-purine-DNA Glycosylase by 3,N4-Ethenocytosine, a Lipid Peroxidation-induced DNA Adduct", Journal of Biological Chemistry, vol. 279, n° 17, p. 17723-17730, April 2004


MORGAN M. et al., "YY1 Regulates the Neural Crest-associated slug Gene in Xenopus laevis", Journal of Biological Chemistry, vol. 279, n° 45, p. 46826-46826, November 2004


DI GIUSTO D. et al., "Construction, Stability, and Activity of Multivalent Circular Anticoagulant Aptamers", Journal of Biological Chemistry, vol. 279, n° 45, p. 46483-46489, November 2004



  • Online ordering: The most convenient way to order your oligonucleotides, peptides and Real-Time qPCR kits is to use our web ordering system. To place orders online, simply login if you have already an online account.

    New online customers ? Not registered yet ? Request your free login and password.

  • By e-mail: order@eurogentec.com
  • By fax : +32 4 264 07 88
  • By mail
    Eurogentec S.A.
    LIEGE Science Park
    Rue du Bois Saint Jean 5
    4102 Seraing
    BELGIUM

If you still have questions with ordering please contact our Customer Support : +32 4 372 76 65.

To receive relevant information on our products, you should first select your country :
Country selection page