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Uracyl-N-glycosylase

Research Diagnostic Therapeutic
Uracil DNA glycosylase (uracil-N-glycosylase) is the product of the Escherichia coli ung gene, and has been cloned and expressed in E. coli . Uracil DNA glycosylase(UDG) removes uracil residues from DNA (single- and double-stranded) without destroying the DNA sugar-phosphodiester backbone, thus preventing its use as a hybridization target or as a template for DNA polymerases. The resulting abasic sites are susceptible to hydrolytic cleavage at elevated temperatures. Thus, removal of uracil bases is usually accompanied by fragmentation of the DNA.


Name Concentration Quantity Reference EUR
Uracyl-N-glycosylase 1000 U/ml 300 Units RT-0610-03 174.00
Uracyl-N-glycosylase 1000 U/ml 1500 Units RT-0610-15 827.00


Delivery times

   2 working days

Shipping conditions

   -20°C

Storage conditions

   -20°C

Uracil DNA glycosylase (uracil-N-glycosylase) is the product of the Escherichia coli ung gene, and has been cloned and expressed in E. coli . Uracil DNA glycosylase(UDG) removes uracil residues from DNA (single- and double-stranded) without destroying the DNA sugar-phosphodiester backbone, thus preventing its use as a hybridization target or as a template for DNA polymerases. The resulting abasic sites are susceptible to hydrolytic cleavage at elevated temperatures. Thus, removal of uracil bases is usually accompanied by fragmentation of the DNA.

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