DNA bases
The fact that each organism possesses its own DNA arouses the scientist interest. The most common method for studying DNA is PCR involving synthetic DNA ...
RNA bases
The solid phase synthesis of RNA fragments is now a widespread technique in Molecular Biology. RNA oligonucleotides are becoming increasingly important ...
LNA® bases
Locked Nucleic Acid (LNA®) was first described by Wengel and co-workers in 1998 as a novel class of conformationally restricted oligonucleotide analogues ...
2' O-Me RNA
Oligo-2’ O-Methyl (O-Me) nucleotides are resistant (but not totally resistant) to a variety of ribo- and deoxyribonucleases. As well as being stable ...
PNA bases
In 1991, Nielsen, Egholm, Berg, and Buchardt reported the synthesis of peptide nucleic acids (PNA), a new, completely artificial DNA/RNA analog in which ...
Phosphorothioate linkages
Phosphorothioate bonds are phosphodiester analogues in which a non-bridging oxygen has been replaced by sulphur. The increased resistance of backbones ...
Methylphosphonate linkages
In contrast to negatively charged phosphodiester bonds, methylphosphonate links are non-ionic nuclease resistant linkages. Methylphosphonate bonds are ...
DNA bases
The fact that each organism possesses its own DNA arouses the scientist interest. The most common method for studying DNA is PCR involving synthetic DNA ...
RNA bases
The solid phase synthesis of RNA fragments is now a widespread technique in Molecular Biology. RNA oligonucleotides are becoming increasingly important ...
LNA® bases
Locked Nucleic Acid (LNA®) was first described by Wengel and co-workers in 1998 as a novel class of conformationally restricted oligonucleotide analogues ...
2' O-Me RNA
Oligo-2’ O-Methyl (O-Me) nucleotides are resistant (but not totally resistant) to a variety of ribo- and deoxyribonucleases. As well as being stable ...
PNA bases
In 1991, Nielsen, Egholm, Berg, and Buchardt reported the synthesis of peptide nucleic acids (PNA), a new, completely artificial DNA/RNA analog in which ...
Phosphorothioate linkages
Phosphorothioate bonds are phosphodiester analogues in which a non-bridging oxygen has been replaced by sulphur. The increased resistance of backbones ...
Methylphosphonate linkages
In contrast to negatively charged phosphodiester bonds, methylphosphonate links are non-ionic nuclease resistant linkages. Methylphosphonate bonds are ...