2’O-Me RNA are partially resistant to a variety of ribo- and deoxyribonucleases. They form more stable hybrids with complementary RNA strands than equivalent DNA/RNA sequences. They are ideal for antisense probes.
Phosphorothioate bonds possess an increased resistance against nucleases due to the substitution of a non-bridging oxygen by sulphur.
Length: From 5 to 139 bases
Synthesis scale: 40 nmol - 200 nmol - 1000nmol - 2.5 µmol - 5µmol - 10 µmol - 20 µmol (Larger quantities available on request)
Modifications: More than 300 modifications available
Purifications: SePOP desalting, HPLC, PAGE, Dual HPLC
Quality Control: MALDI-TOF MS
Format: Dried. other formats on option
Packaging: 2 mL tube, 96-well or 384-well plates. Higher scales from 2.5 µmol may be delivered in 50mL tubes.