Oligos

5'-DBCO-TEG - 1 modification

134.00
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  • Cat.Number : MD-MF080-05020
  • Availability :
    In production

Synthesis scale

DBCO is a biorthogonal functional group which reacts with azides in Copper Free Click Reactions.
DBCO-TEG is a Dibenzo-bicyclo-octyne (DBCO) structure with a Triethyleneglycol (TEG) spacer. The TEG spacer separates the hydrophobic moiety (DBCO) from the linked oligo
Bioorthogonal chemistry such as Copper Free Click reaction enables chemical reactions to be performed in living system keeping intact the system biology. This is a powerful method to conjugate and assemble molecules in vivo to detect and/or treat diseases.

Specifications

Chemistry
Molecular Mass/ Weight
  • 570.57
Modification
Modification Position
  • 5'
Storage & stability
Resuspension condition
  • -Spin the tube briefly to collect the pellet in the bottom of the tube - Add an appropriate volume of recommended buffer (refer to technical data sheet) - Allow the tube to stand a few minutes - Vortex the tube for 15 seconds
Storage Conditions
  • Dried Oligonucleotides are stable for 18 months at ambiant temperature. Oligonucleotides in solutions are stable for 24 months at -20°C. (Tolerance -20°C± 5°C. )For more information please refer to the Reconstitution-Storage-Stability page<br>
Codes
Code Nacres
  • NA.51

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Citations

Multiplex enzymatic synthesis of DNA with single-base resolution

Science Advances . 2023 Jul 07 ; 9 | DOI : https://doi.org/10.1126/sciadv.adi0263

  • Damiano Verardo
  • et al