DBCO is a biorthogonal functional group which reacts with azides in Copper Free Click Reactions.
DBCO-TEG is a Dibenzo-bicyclo-octyne (DBCO) structure with a Triethyleneglycol (TEG) spacer. The TEG spacer separates the hydrophobic moiety (DBCO) from the linked oligo
Bioorthogonal chemistry such as Copper Free Click reaction enables chemical reactions to be performed in living system keeping intact the system biology. This is a powerful method to conjugate and assemble molecules in vivo to detect and/or treat diseases.