Oligos

Alexa488-labeled C-rich telomere probe - 5 nmol

450,00
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  • Cat.Number : PN-TC060-005
  • Availability :
    In production

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The sequence of the Alexa 488-labeled C-rich telomere probe is constituted of CCCTAA repeats and is 5' labeled by the Alexa 488 fluorescent Dye. The sequence is specific for both human and mouse

In principle, fluorescence in situ hybridisation (FISH) should be able to provide information on telomere length of individual chromosomes. However the efficiency of DNA/RNA oligonucleotide hybridizations for telomeric repeats investigation is not sufficient. In comparison the use of PNA stabilizes PNA-DNA/RNA duplexes. When used with PNA probes, PNA-DNA hybridization is much faster within a couple of hours and results in significantly reduced background noise due to the high signal to background noise ratio.

* The PNA bases are only available in the following countries: Belgium, France, Germany, Italy, Luxembourg, Netherlands, Denmark, Ireland, United Kingdom, Greece, Portugal, Spain, Austria, Finland, Sweden, Cyprus, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Malta, Poland, Slovakia, Slovenia, Bulgaria, Romania, Norway, Iceland, Bosnia, Serbia, Montenegro, Turkey, Switzerland, Israel, Russia and African countries.

Specifications

Packaging
Kits components
  • 1 x 2ml tube containing 5 nmol of lyophilised probe
Chemistry
Sequence one letter code
  • repeats of CCCTAA
Properties
Absorbance (nm)
  • 495
Emission (nm)
  • 519
Modification
Modification Position
  • 5'
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Storage & stability
Form
  • Dried
Resuspension condition
  • Please refer to the protocol
Activity
Detection Method
Usage
  • Research use

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