Peptides

Buforin 2 - 1 mg

162,00
Check your price
  • Cat.Number : AS-61255
  • Availability :
    In stock

Quantity

This peptide, also referred to as Buforin II peptide is a 21 amino acid peptide derived from Buforin I peptide that is isolated from the Asian toad Bufo gargarizans. The 21 amino acid peptide has been shown to possess anti-microbial activity by penetrating bacteria and inhibiting cellular functions. This antimicrobial peptide interacts with phospholipid bilayers and can be efficiently translocated accross the layer with a weak membrane permeabilization activity. The proline hinge in Buforin 2 is responsible for these cell penetrating properties. This class of antibacterial peptides therefore targets intracellular molecules, most probably nucleic acids, without significantly permeting cell membranes.
In comparison to magainin 2, this peptide binds DNA and RNA from E.coli with a much greater affinity. It is also considered a cell-delivery peptide and has been shown to deliver SiRNAs into cells followed by effective mRNA degradation.

Specifications

Chemistry
Sequence one letter code
  • TRSSRAGLQFPVGRVHRLLRK
Sequence three letter code
  • Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys
CAS registry number
  • 172998-24-2
Molecular Formula
  • C106H184N40O26
Molecular Mass/ Weight
  • 2434.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • toad

You may also be interested in the following product(s)

Tube of (Arg)9 peptide

(Arg)9 - 1 mg

Cat.Number : AS-61204
56,00
Tube of FITC-LC-Antennapedia Peptide

FITC-LC-Antennapedia Peptide

Cat.Number : AS-24175
149,00
Tube of TAT (47-57) peptide, TAMRA-labeled

TAT (47-57), TAMRA-labeled - 1 mg

Cat.Number : AS-61211
213,00