Peptides

c-Myc peptide epitope

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  • Cat.Number : AS-20590
  • Availability :
    In stock

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c-Myc, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope.

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • EQKLISEEDL
Sequence three letter code
  • H-Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-OH
Molecular Formula
  • C51H86N12O21
Molecular Mass/ Weight
  • 1203.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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Citations

Improved β-Elimination-Based Affinity Purification Strategy for Enrichment of Phosphopeptides.

Anal Chem . 2003 Dec 15 ; 75(24) 6826 | DOI : 10.1021/ac034989u

  • D. McLachlin
  • et al