Peptides

Cls Substrate, C2 (Abz/Dnp) - 1 mg

176.00
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  • Cat.Number : AS-61315
  • Availability :
    In production

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Quantity

This peptide is a second complement component (C2), the physiological substrate for the proenzyme Cls, first complement component. The complement system is a central component of host defense but can also contribute to the inflammation seen in pathological conditions. The C1s protease of the C1 complex initiates the host defense pathway. This peptide employs 2Abz/Dnp FRET pair for quantitation of complement enzyme activity.

Specifications

Chemistry
Sequence one letter code
  • 2Abz-SLGRKIQIK(Dnp)-NH2
Sequence three letter code
  • 2Abz-Ser-Leu-Gly-Arg-Lys-Ile-Gln-Ile-Lys(Dnp)-NH2
Molecular Mass/ Weight
  • 1326.6
Properties
Absorbance (nm)
  • 320
Emission (nm)
  • 420
Modification
Conjugation type
  • Double dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • synthetic
Codes
Code Nacres
  • NA.26

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Citations

Antimicrobial peptide conformation as a structural determinant of omptin protease specificity

J Bacteriol . 2015 Sep 08 ; 197 22 | DOI : 10.1128/JB.00469-15

  • RJ. Brannon
  • et al

OmpT outer membrane proteases of enterohemorrhagic and enteropathogenic Escherichia coli contribute differently to the degradation ofhuman LL-37

Infect Immun . 2011 Dec 05 ; 80(2) 483 | DOI : 10.1128/​IAI.05674-11

  • JL. Thomassin
  • et al