Peptides

epsilon-V1-2, PKCe Inhibitor, Cys-conjugated - 1 mg

83.00
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  • Cat.Number : AS-62187
  • Availability :
    In stock

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Quantity

This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • EAVSLKPTC
Sequence three letter code
  • H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-Cys-OH
Molecular Formula
  • C40H70N10O14S1
Molecular Mass/ Weight
  • 947.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, mouse, rat, bovine
Codes
Code Nacres
  • NA.26

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