Peptides

Gastrin-1, human - 1 mg

127.00
Check your price
  • Cat.Number : AS-20750
  • Availability :
    In production

Select specification

Quantity

Gastrin-1 is also referred to as Gastrin-17 or “Little Gastrin.” Secretion of gastrin is induced by food intake and causes the release of gastric acid in the stomach. Secreted by the G cells in the gastric mucosa, it is one of the major bioactive forms of gastrin found in tissue and plasma (the other bioactive form is Gastrin-34 or Big Gastrin). Both Gastrin-17 and Gastrin-34 are carboxy-amidated and partially tyrosine sulfated. Binding of Gastrin to the CCK2/gastrin receptor requires carboxy-amidation, however sulfation is not necessary for binding to the receptor. Binding of Gastrin to the CCK2/Gastrin receptors on parietal cells of the stomach causes them to secrete hydrochloric acid (HCl) and stimulates lectin-like protein Reg expression via activation of PKC and RhoA. Gastrin also plays a role in release of Histamine and Pepsinogen.

Specifications

Chemistry
Sequence one letter code
  • Pyr-GPWLEEEEEAYGWMDF-NH2
Sequence three letter code
  • Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
CAS registry number
  • 10047-33-3
Molecular Formula
  • C97H124N20O31S
Molecular Mass/ Weight
  • 2098.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

You may also be interested in the following product(s)

Tube of Leptin (93-105) peptide, human

Leptin (93-105), human - 1 mg

Cat.Number : AS-62853
83.00 Excl. Tax
Tube of Secretin peptide, rat

Secretin, rat - 1 mg

Cat.Number : AS-60677
219.00 Excl. Tax
Image of a kit SensoLyte 520 Enterokinase Assay Kit Fluorimetric

SensoLyte® 520 Enterokinase Assay Kit Fluorimetric - 1 kit

Cat.Number : AS-72209
509.00 Excl. Tax

Citations

Mesenchymal Cells Appearing in Pancreatic Tissue Culture Are Bone Marrow-Derived Stem Cells With the Capacity to Improve Transplanted Islet Function.

Stemm Cells . 2010 Jan 01 ; 28(1) 140 | DOI : 10.1002/stem.259

  • V. Sordi
  • et al

Omeprazole and PGC-formulated heparin binding epidermal growth factor normalizes fasting blood glucose and suppresses insulitis in multiple low dose Streptozotocin diabetes model.

Pharm Res . 2013 Jun 11 ; 30(11) 2843 | DOI : 10.1007/s11095-013-1112-6

  • GM. Castillo
  • et al