Peptides

IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide - 1 mg

162,00
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  • Cat.Number : AS-61169
  • Availability :
    In stock

Quantity

A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IK?NEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.

Specifications

Chemistry
Sequence one letter code
  • DRQIKIWFQNRRMKWKKTALDWSWLQTE
Sequence three letter code
  • H-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-Glu-OH
Molecular Formula
  • C170H259N49O42S
Molecular Mass/ Weight
  • 3693.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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