Peptides

IL-8 Inhibitor - 1 mg

66,00
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  • Cat.Number : AS-62401
  • Availability :
    In stock

Quantity

This hexapeptide, acetylated on the amino terminus and amidated on the carboxyl terminus, inhibits the specific binding of 125I-IL-8 to neutrophils. IL-8 is a member of the chemokine alpha subfamily that activates neutrophils and is chemotactic for these cells. IL-8 Inhibitor also suppresses the binding of macrophage inflammatory protein 2 (MIP 2) beta to neutrophils.

Specifications

Chemistry
Sequence one letter code
  • Ac-RRWWCR-NH2
Sequence three letter code
  • Ac-Arg-Arg-Trp-Trp-Cys-Arg-NH2
CAS registry number
  • 138559-60-1
Molecular Formula
  • C45H66N18O7S
Molecular Mass/ Weight
  • 1003.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

Direct Elucidation of disulfide bond partners using ultraviolet photodissociation mass spectrometry.

Anal Chem . 2011 Aug 02 ; 83(17) 6455 | DOI : 10.1021/ac201650v

  • A. Agarwal
  • et al

Mechanism of neutrophil recruitment to the lung after pulmonary contusion.

Shock . 2011 Jun 01 ; 35(6) 604 | DOI : 10.1097/SHK.0b013e3182144a50

  • JJ. Hoth
  • et al

Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy antigen receptor for chemokines.

J Leukocyte Biol . 2009 Sep 10 ; 86(6) 1385 | DOI : 10.1189/jlb.0309183

  • M. Zerfaoui
  • et al