Peptides

Integrin-Binding Site, GRGDNP - 1 mg

56,00
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  • Cat.Number : AS-62049
  • Availability :
    In stock

Quantity

This RGD-containing sequence is integrin-binding site. RGD peptides are found in both extracellular matrix (ECM) (e.g., collagen, osteopontin, fibronectin, and vitronectin) and non-ECM proteins (e.g., disintegrins). RGD-containing peptides are recognized by several integrins. This peptide targets both alphavbeta3 and alpha5beta1 integrins. Interaction of the RGDN sequence with endothelial alpha5beta1 integrin causes endothelin-mediated arteriolar vasoconstriction. This peptide influences the IkappaB kinase (IKK)/nuclear factor-kappaB (NF-kappaB) activation. It also controls the cardiac contractile function.

Specifications

Chemistry
Sequence one letter code
  • GRGDNP
Sequence three letter code
  • H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS registry number
  • 114681-65-1
Molecular Formula
  • C23H38N10O10
Molecular Mass/ Weight
  • 614.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • synthetic

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