Oligos

LNA® Base Phosphorothioate Linkage - 1 base with PTO Linkage

24.70
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  • Cat.Number : BA-LN010-004
  • Availability :
    In production

Synthesis scale

Alternative choices

LNA® (Locked Nucleic Acid) is a bicyclic nucleic acid with a structure locked into a rigid C3'-endo position, which favours RNA A-type helix duplex geometry.
This exceptional structure confers a very strong thermal stability towards complementary DNA and RNA template suitable for hybridization assays requiring high specificity and/or reproducibility.

Phosphorothioate bonds possess an increased resistance against nucleases due to the substitution of a non-bridging oxygen by sulphur.

Length: From 5 to 139 bases
Synthesis scale: 40 nmol - 200 nmol - 1000nmol - 2.5 µmol - 5µmol - 10 µmol - 20 µmol (Larger quantities on request)
Modifications: More than 300 modifications available
Purifications: SePOP desalting, RP-Cartridge-Gold™, HPLC, PAGE, Dual HPLC
Quality Control: MALDI-TOF MS
Format: Dried. other formats on option
Packaging: 2 mL tube, 96-well or 384-well plates. Higher scales from 2.5 µmol may be delivered in 50mL tubes.

Specifications

Chemistry
Linkage
  • Phosphorothioate Linkage
Molecular Mass/ Weight
  • -
Modification
Modification Position
  • 3'
  • 5'
  • IN
Storage & stability
Resuspension condition
  • - Spin the tube briefly to collect the pellet in the bottom of the tube - Add an appropriate volume of recommended buffer (refer to technical data sheet) - Allow the tube to stand a few minutes - Vortex the tube for 15 seconds
Storage Conditions
  • Dried Oligonucleotides are stable for 18 months at ambiant temperature. Oligonucleotides in solutions are stable for 24 months at -20°C. (Tolerance -20°C± 5°C. ) For more information please refer to the Reconstitution-Storage-Stability page
Activity
Usage
  • Research use
Codes
Code Nacres
  • NA.51

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