SensoLyte® Anti-PLP (139-151) IgG Quantitative ELISA Kit (mouse) Colorimetric - 1 kit

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  • Cat.Number : AS-55524
  • Availability :
    In production
  • Shipping conditions : Ice delivery fees must be applied

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Proteolipid protein (PLP) is the most abundant protein in the central nervous system (CNS) myelin sheath and is highly conserved among species. PLP has a 50% hydrophobic amino acids content and a molecular weight of 30 kDa. Mouse PLP (139-151) is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to mouse PLP (139-151) has been observed in induced experimental autoimmune encephalomyelitis (EAE) in SJL, F1, and SWR mice strains. However, the exact pathological role
and action of anti-mouse PLP (139-151) autoantibody is not well understood.
The SensoLyte® Anti-PLP (139-151) IgG Quantitative ELISA Kit (mouse) provides a convenient and quantitative assay for anti-PLP (139-151) autoantibody in mouse. This kit is useful to researchers who wants to determine the amount of anti-PLP (139-151) antibody present in biological samples, and can help provide information on the role it plays in the development and treatment of EAE, an animal model for MS pathogenesis.


Kits components
  • Component A: PLP (139-151) coated and BSA blocked 8-well strips: 12 x 8 strips Component B: Mouse anti-PLP (139-151) IgG Standard: 100 µl (20 µg/ml) Component C: 1X Sample Dilution Buffer: 30 ml Component D: 10X Wash Buffer: 50 ml Component E: TMB color substrate solution: 10 ml Component F: Stop Solution: 10 ml Component G: Secondary antibody, Goat anti-Mouse IgG-HRP: 30 µl
UniProt number
  • P60202
Storage & stability
Storage Conditions
  • Store all other components at 4°C for up to 6 months. Store component B at -20°C in small aliquots. Protect components E and G from light.
Biomarker Target
Detection Method
Detection Limit
  • 100 pg
  • mouse
Research Area
Sub-category Research Area
  • Research use
Code Nacres
  • NA.32

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