SensoLyte® Fluorescent ß-Amyloid (1-42) Sampler Kit - 1 kit

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  • Cat.Number : AS-72071
  • Availability :
    In stock
  • Shipping conditions : Ice delivery fees must be applied


Fluorophore labeled beta-amyloid peptides have been used in investigating beta-amyloid's aggregation, generation and clearance, microglial activation and phagocytosis. The SensoLyte® Fluorescent beta-Amyloid (1-42) Sampler Kit provides three fluorescent beta-amyloid (1-42) peptides, two unlabeled control peptides and biotin labeled beta-amyloid (1-42) peptide. The sampler kit provides ample choices for researchers interested in beta-amyloid related experiments

Alzheimer's Disease (AD) is the most common neurodegenerative disorder in elderly people. It has been demonstrated that AD has biological causes and is characterized by the presence of senile plaques and neurofibrillary tangles mainly in cerebral cortex and hippocampus brain regions. Beta-Amyloid (1-40) (Aα40) and beta-Amyloid (1-42) (Aα42) are the main components of the above plaques; however, other forms of beta-Amyloid peptides are also present. Both peptides are cleaved from the Amyloid Precursor Protein (APP) by α-secretase and γ-secretase enzymes. Many studies suggest that Aα42 or/and Aα43 are required to initiate formation of amyloid plaques and neurofibrills that leads to the neurodegeneration, while Aα40 is less neurotoxic.


Kits components
  • Component A: 6 peptides (each as lyophilized powder): - Two unlabeled control peptides: AS-24224 (ß-amyloid 1-42), AS-25382 (scrambled ß-amyloid 1-42) - A biotin labeled ß-amyloid 1-42 peptide: AS-23524 (biotin-ß-amyloid 1-42) - Three ß-amyloid 1-42 peptides with different fluorophore conjugates: AS-23526 (FAM-ß-amyloid 1-42; 494/521nm); AS-60479 (HiLyte™ Fluor 488-ß-amyloid 1-42; 503/528nm); AS-60476 (TAMRA-ß-amyloid 1-42; 544/572nm) Component B: Solvent for ß-amyloid 1-42 (1 mL)
UniProt number
  • P05067
Absorbance (nm)
  • 494/503/544
Emission (nm)
  • 521/528/572
Quantity & Purity
  • ≥ 95%
Storage & stability
  • Lyophilized
Storage Conditions
  • Store component A at -20°C and protect from light and moisture. Component B can be stored at 4°C.
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
  • Research use
Source / Species
  • human
Code Nacres
  • NA.32

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