Peptides

Shepherdin (79–87) - 1 mg

66,00
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  • Cat.Number : AS-62748
  • Availability :
    In stock

Quantity

This is amino acids 79 to 87 fragment of shepherdin, a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability. For its potent and broad antitumor activity, selectivity of action in tumor cells versus normal tissues, and inhibition of tumor growth in vivo without toxicity, shepherdin may offer a promising approach for rational cancer therapy. This sequence is also known as K79–K90.

Specifications

Chemistry
Sequence one letter code
  • KHSSGCAFL
Sequence three letter code
  • H-Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu-OH
CAS registry number
  • 861224-28-4
Molecular Formula
  • C41H64N12O12S
Molecular Mass/ Weight
  • 949.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, pig, dog

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Citations

A Bombesin-Shepherdin radioconjugate designed for combined extra-and intracellular targeting

Pharmaceuticals (Basel).  . 2014 May 27 ; 7(6) 662 | DOI : 10.3390/ph7060662

  • CA. Fischer
  • et al