Peptides

TAT (47-57) GGG-Cys(Npys) - 1 mg

240.00
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  • Cat.Number : AS-61215
  • Availability :
    In stock

Quantity

This is the most characterized fragment of the HIV transactivator protein (TAT). This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis.
This peptide corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. The N-terminus is rendered free for applications requiring certain conjugation reactions with a free N-terminal end, and a linker GGG is placed at the C-terminal end, and the peptide has been synthesized with the C(Npys) group. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies.

Specifications

Chemistry
Sequence one letter code
  • YGRKKRRQRRRGGG-C(Npys)-NH2
Sequence three letter code
  • H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Cys(NPYS)-NH2
Molecular Formula
  • C78H135N39O19S2
Molecular Mass/ Weight
  • 1987.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HIV
Codes
Code Nacres
  • NA.26

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