Peptides

TIF2 (740-753), Transcriptional Intermediary Factor 2 - 1 mg

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  • Cat.Number : AS-61992
  • Availability :
    In stock

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This peptide is a nuclear receptor (NR) box B3 region of the p160 co-activator Transcriptional Intermediary Factor 2 (TIF2) peptide, a LXXLL motif. The activation function 2/ligand-dependent interaction between nuclear receptors and their co-regulators is mediated by a short consensus motif nuclear receptor box.

Specifications

Chemistry
Sequence one letter code
  • KENALLRYLLDKDD
Sequence three letter code
  • H-Lys-Glu-Asn-Ala-Leu-Leu-Arg-Tyr-Leu-Leu-Asp-Lys-Asp-Asp-OH
Molecular Formula
  • C75H124N20O25
Molecular Mass/ Weight
  • 1705.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, mouse, rat

Citations

Agonist versus antagonist induce distinct thermodynamic modes of co-factor binding to the glucocorticoid receptor

Biophys Chem.  . 2007 Apr 05 ; 128(2-3) 156 | DOI : 10.1016/j.bpc.2007.03.013

  • R. Kroe
  • et al