Peptides

[Trp63, 64]-C3a (63-77) - 1 mg

100.00
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  • Cat.Number : AS-61119
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    In stock

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This peptide, which is a C-terminal analogue of the complement factor C3a, acts as an agonist to the C3a receptor. It is derived from the fifteen C-terminal residues (6-77) of C3a. In in vitro studies, both C 3a and this peptide have been shown to selectively bind to C3aRs and induce degranulation of C3aR-transfeted RBL-2H3 cells. There was also a rapid, transient and concentration-dependent hypertensive response observed in rats when infused intravenously with C3a and this peptide.

Specifications

Chemistry
Sequence one letter code
  • WWGKKYRASKLGLAR
Sequence three letter code
  • H-Trp-Trp-Gly-Lys-Lys-Tyr-Arg-Ala-Ser-Lys-Leu-Gly-Leu-Ala-Arg-OH
CAS registry number
  • 130154-64-2
Molecular Formula
  • C86H134N26O18
Molecular Mass/ Weight
  • 1820.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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Citations

Parallel detection of intrinsic fluorescence from peptides and proteins for quantification during mass spectrometric analysis

Anal Chem . 2011 Mar 15 ; 83(6) 2187 | DOI : 10.1021/ac103023q

  • J. Russell
  • et al