Peptides

ß-Secretase Inhibitor 1 - 1 mg

181.00
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  • Cat.Number : AS-23958
  • Availability :
    In stock

Quantity

ß-Secretase (BACE1) is a key enzyme involved in the production of Aß peptides found in extracellular amyloid plaques of Alzheimer’s disease (AD). The enzyme has been implicated as an excellent target for anti-amyloid therapy of AD. This statine-based substrate analog, beta-secretase inhibitor P10–P4’ statV, is used in the inhibition of beta-secretase activity from homogenized wild-type mouse cortices and from BACE-purified from human brain.

Specifications

Chemistry
Sequence one letter code
  • KTEEISEVN-Sta-VAEF (Sta = statine)
Sequence three letter code
  • H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe-OH
CAS registry number
  • 350228-37-4
Molecular Formula
  • C73H118N16O27
Molecular Mass/ Weight
  • 1652
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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