3' Thiol (-SH) C3 - 1 modification

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  • Cat.Number : MD-MF053-03004
  • Availability :
    In production

Synthesis scale

Alternative choices

Thiol group (reduced form -SH) can be linked to the 5’ or 3’ terminus of an oligonucleotide. This modification is used for oligo activation prior to linking to various types of molecules or support. The thiol groups can be used to attach a variety of products to the oligonucleotide. Common thiol-reactive groups include maleimides, halogens, iodoacetamides and pyridyldisulfides. This DNA modification is commonly used for the attachment of enzymes such as horseradish peroxidase or alkaline phosphatase.
3' thiol C3 S-S and 3' thiol C6 S-S Thiol (not reduced -SS form) are also available on request.


Spacers Sequence
  • C3
Molecular Mass/ Weight
  • 154,12
Modification Position
  • 3'
Storage & stability
Resuspension condition
  • - Spin the tube briefly to collect the pellet in the bottom of the tube - Add an appropriate volume of recommended buffer (refer to technical data sheet) - Allow the tube to stand a few minutes - Vortex the tube for 15 seconds
Storage Conditions
  • Dried Oligonucleotides are stable for 18 months at ambiant temperature. Oligonucleotides in solutions are stable for 24 months at -20°C. (Tolerance -20°C± 5°C. ) For more information please refer to the Reconstitution-Storage-Stability page
  • Research use
Code Nacres
  • NA.51

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