Peptides

390 MMP FRET Substrate 5 - 1 mg

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  • Cat.Number : AS-62027
  • Availability :
    In stock

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Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a substrate for the MMP-12, macrophage elastase, Abs/Em = 325/393 nm. MMPs are considered to be critical mediators of both normal and pathological tissue remodeling processes.

Specifications

Chemistry
Sequence one letter code
  • Mca-PLGLEEA-Dap(Dnp)-NH2
Sequence three letter code
  • Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2
CAS registry number
  • 891198-38-2
Molecular Formula
  • C53H70N12O20
Molecular Mass/ Weight
  • 1193.2
Properties
Absorbance (nm)
  • 325
Emission (nm)
  • 393
Modification
Conjugation type
  • Double dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use

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