Peptides

520 MMP FRET Substrate 12 - 0.1 mg

162,00
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  • Cat.Number : AS-60579-01
  • Availability :
    In stock

Quantity

Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12 and 13 activities, Abs/Em = 494/521 nm.

Specifications

Chemistry
Sequence one letter code
  • 5-FAM-RPKPYA-Nva-WM-K(QXL® 520)-NH2
Sequence three letter code
  • 5-FAM-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(QXL® 520)-NH2
Molecular Mass/ Weight
  • 2125.4
Properties
Absorbance (nm)
  • 494
Emission (nm)
  • 521
Modification
Conjugation type
  • Double dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use

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