Peptides

C-peptide, dog - 0.5 mg

143.00
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  • Cat.Number : AS-61128
  • Availability :
    In stock

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Quantity

Insulin secretory rate can be estimated from peripheral C-peptide concentrations in dogs. Plasma C-peptide concentrations during glucagon stimulation testing is variable in diabetic dogs and may represent dogs with type-1 and type-2 diabetes or more likely, differences in severity of b-cell loss in dogs with type-1 diabetes.

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • EVEDLQVRDVELAGAPGEGGLQPLALEGALQ
Sequence three letter code
  • H-Glu-Val-Glu-Asp-Leu-Gln-Val-Arg-Asp-Val-Glu-Leu-Ala-Gly-Ala-Pro-Gly-Glu-Gly-Gly-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ala-Leu-Gln-OH
CAS registry number
  • 39016-05-2
Molecular Formula
  • C137H225N37O49
Molecular Mass/ Weight
  • 3174.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • dog
Codes
Code Nacres
  • NA.26

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