Peptides

Calpain Inhibitor Peptide, B27-WT - 0.5 mg

106,00
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  • Cat.Number : AS-60844
  • Availability :
    In stock

Quantity

Calpains are a family of intracellular Ca2+ dependent cysteine proteases. They respond to Ca2+ signals by cleaving many specific proteins, thereby irreversibly modifying their function(s). They are implicated in a variety of Ca2+ regulated cellular processes as well as various pathological phenomena, such as ischemic injury, muscular dystrophy, diabetes, cataract, atherosclerosis, Alzheimer’s disease, and cancer. Calpains represent potential therapeutic targets for drug discovery.
This 27-residue peptide is derived from subdomain 1B of the repetitive domains of calpain, named peptide B27-WT. It is a potent inhibitor of calpain.

Specifications

Chemistry
Sequence one letter code
  • DPMSSTYIEELGKREVTIPPKYRELLA
Sequence three letter code
  • H-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-OH
CAS registry number
  • 128578-18-7
Molecular Formula
  • C140H227N35O44S
Molecular Mass/ Weight
  • 3136.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, monkey

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