Peptides

DNA-PK Substrate - 5 mg

362.00
Check your price
  • Cat.Number : AS-60210-5
  • Availability :
    In stock

Quantity

A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11–24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activity

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • EPPLSQEAFADLWKK
Sequence three letter code
  • H-Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys-OH
Molecular Formula
  • C82H123N19O24
Molecular Mass/ Weight
  • 1759.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

You may also be interested in the following product(s)

Tube of CREBtide peptide, 5-FAM

CREBtide [KRREILSRRPSYR], 5-FAM labeled

Cat.Number : AS-60436-1
246.00 Excl. Tax
Tube of Glasstide peptide, PKG substrate

PKG Substrate [RKRSRAE], Glasstide

Cat.Number : AS-60298-1
88.00 Excl. Tax