Peptides

HIV Substrate, HiLyte™ Fluor 488 - 0.1 mg

106,00
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  • Cat.Number : AS-60635
  • Availability :
    In stock

Quantity

Ths is a HiLyte Fluor labeled HIV protease substrate I, GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS. The peptide sequence is derived from the native p17/p24 cleavage site on HIV precursor polyprotein Prgag for HIV-1 protease. Cleavage of HIV precursor polyproteins is essential for the maturation of the infectious virus and hence the protease has become a major target for developing anti-AIDS drugs. The peptide substrate is widely used for the continuous assay for HIV protease activity. The QXL/488 pair offers better sensitivity in detection at a higher wavelength with less background interference. (Excitation/Emission = 490 nm/520 nm).

Specifications

Chemistry
Sequence one letter code
  • QXL®520-GABA-SQNYPIVQ-K(HiLyte™ Fluor 488)-NH2
Sequence three letter code
  • QXL® 520-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(Hilyte™ Fluor 488)-NH2
Molecular Mass/ Weight
  • 2008.1
Properties
Absorbance (nm)
  • 490
Emission (nm)
  • 520
Modification
Conjugation type
  • Double dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HIV

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