Peptides

IRBP, Interphotoreceptor Retinoid Binding Protein Fragment

122.00
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  • Cat.Number : AS-60183-1
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This 20-residue peptide, a major pathogenic T-cell epitope (161–180), is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).

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Citations

Low dose rapamycin exacerbates autoimmune experimental uveitis.

Plos One . 2012 May 04 ; 7(5) e36589 | DOI : 10.1371/journal.pone.0036589

  • Z. Zhang
  • et al

Role of DAF in protecting against T-cell autoreactivity that leads to experimental autoimmune uveitis.

Invest Ophthalmol Vis Sci. . 2009 May 14 ; 50(8) 3778 | DOI : 10.1167/iovs.08-3264

  • F. An
  • et al

Autoimmune uveitis elicited with antigen-pulsed dendritic cells has a distinct clinical signature and is driven by unique effector mechanisms: initial encounter with autoantigen defines disease phenotype.

J Immunol. . 2007 May 01 ; 178(9) 5578 | DOI : 10.4049/jimmunol.178.9.5578

  • Jung Tan
  • et al