Peptides

[Lys(Me3)4]-Histone H3 (1-21)-GGK(Biotin)-NH2 - 1 mg

294,00
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  • Cat.Number : AS-64192
  • Availability :
    In stock

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This peptide is a synthetic peptide corresponding to amino acids 1-21 of human histone H3. It is trimethylated at lysine-4 with a C-terminal Gly-Gly linker followed by a biotinylated Lys. The trimethylation of histone H3 at lysine 4 [H3K4(Me3)] shows cell state and lineage potential by differentiating genes that are expressed, poised for expression, or repressed. H3K4(Me3) also labels imprinting control regions.

Specifications

Chemistry
Sequence one letter code
  • ART-K(Me3)-QTARKSTGGKAPRKQLA-GGK(Biotin)-NH2
Sequence three letter code
  • H-Ala-Arg-Thr-Lys(Me3)-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-NH2
Molecular Mass/ Weight
  • 2765.2
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H327 methylated nucleosomes in brain.

Nucl Acids Res . 2011 Dec 05 ; 40(7) 2884 | DOI : 10.1093/nar/gkr1066.

  • AA. Thambirajah
  • et al