Peptides

Plasmodium falciparum Circumsporozoite Protein, (6NANP) PfCSP - 1 mg

167,00
Check your price
  • Cat.Number : AS-64434
  • Availability :
    In production

Quantity

The P. falciparum circumsporozoite protein (PfCSP) is the most abundant antigen expressed on the surface of P. falciparum sporozoites. This pre-erythrocytic antigen contains a stretch of 6 highly conserved, immunodominant tetrapeptide repeats (NANP) in the middle, while its N- and C-terminal regions contain two crucial protective regions termed RI and RII-plus, respectively. Both play key roles during parasite invasion. PfCSP has been the main target antigen in the development of preerythrocytic malaria vaccines, including subunit proteins with adjuvants or attenuated viral platforms. Studies show that high titers of antibodies directed to PfCSP are believed to interrupt the invasion of hepatocytes by blood-borne sporozoites, thereby abrogating the development of blood-stage malaria.

Specifications

Chemistry
Sequence one letter code
  • NANPNANPNANPNANPNANPNANPC
Sequence three letter code
  • H-Asn-Ala-Asn-Pro-Asn-Ala-Asn-Pro-Asn-Ala-Asn-Pro-Asn-Ala-Asn-Pro-Asn-Ala-Asn-Pro-Asn-Ala-Asn-Pro-Cys-OH
Molecular Formula
  • C99H151N37O38S1
Molecular Mass/ Weight
  • 2499.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Plasmodium

You may also be interested in the following product(s)

Tube of flg22 peptide, Flagellin Fragment

flg22, Flagellin Fragment - 1 mg

Cat.Number : AS-62633
167,00
Tube of hBD-1 peptide, ?-Defensin-1 peptide, human

hBD-1, b-Defensin-1, human - 0.1 mg

Cat.Number : AS-60740
286,00
Tube of LL-37 peptide, human

LL-37, Antimicrobial Peptide, human - 1 mg

Cat.Number : AS-61302
168,00