Peptides

Protegrin-1 (PG-1), amide

312.00
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  • Cat.Number : AS-64819-05
  • Availability :
    In stock

Size

Quantity

This peptide is Protegrin-1 (PG-1) with a modified C-terminal amide. PG-1 is an 18-amino-acid beta-hairpin antimicrobial peptide found in porcine leukocytes and belongs to the cathelicidin family. PG-1 exhibits broad-spectrum activity unaffected by extracellular NaCl concentrations and is capable of inactivating numerous bacterial strains, Candida albicans, and some enveloped viruses. The efficacy is strongly dependent upon the existence of two disulfide bonds that stabilize the beta-sheet structure.

Specifications

Chemistry
Sequence one letter code
  • RGGRLCYCRRRFCVCVGR-NH2 (disulfide bridge:6-15 and 8-13)
Sequence three letter code
  • H-Arg-Gly-Gly-Arg-Leu-Cys-Tyr-Cys-Arg-Arg-Arg-Phe-Cys-Val-Cys-Val-Gly-Arg-NH2 (disulfide bridge:6-15 and 8-13)
Molecular Formula
  • C88H147N37O19S4
Molecular Mass/ Weight
  • 2155.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • porcine
Codes
Code Nacres
  • NA.26

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