Recombinant rat MOG (1-125)
- Cat.Number : AS-55152-100
- Manufacturer Ref. :
- Shipping conditions : Ice delivery fees must be applied
Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys
The sequence (Accession #CAE84068) corresponding to the extracellular domain of rat MOG along with a 6x His tag was expressed in E. coli. The recombinant rat MOG (R-rMOG) was purified from urea denatured bacterial lysate using immobilized metal affinity chromatography (IMAC). The molecular mass of the recombinant rat MOG is 14.2 kDa.
|Molecular Mass/ Weight||
|Quantity & Purity|
|Storage & stability|
|Sub-category Research Area|
|Source / Species||
You may also be interested in the following product(s)
Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity
PLOS . 2012 Mar 30 ; 7(3) e33797 | DOI : 10.1371/journal.pone.0033797.
- U. Schulze-Topphoff
- et al