SensoLyte® 490 HCV Protease Assay Kit Fluorimetric 500 assays - 1 kit
- Cat.Number : AS-71126
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HCV protease is identified as an important drug-screening target. The SensoLyte® 490 HCV Protease Assay Kit uses an optimized FRET peptide substrate for the continuous measurement of HCV NS3/4a activity. This FRET substrate is cleaved specifically by HCV NS3/4a protease thereby liberating the C-terminal peptide-fluorophore fragment from the proximity quenching effect of the dark quencher, resulting in a more than 10-fold increase in fluorescence. This assay can detect HCV NS3/4a protease activity at 1 pmole.
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Citations
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- et al
A method to simultaneously monitor hepatitis C virus NS3 helicase and protease activities.
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- et al