Assay-kits

SensoLyte® 490 MMP-3 Assay Kit Fluorimetric - 1 kit

611,00
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  • Cat.Number : AS-71130
  • Availability :
    In stock
  • Shipping conditions : Ice delivery fees must be applied

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Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion as well as other diseases is well known. MMP-3 (stromelysin-1, transin-1) is proposed as a potential therapeutic target. The SensoLyte® 490 MMP-3 Assay Kit is a complete assay system designed to continuously analyze MMP activities or to screen MMP-3 inhibitors using a fluorogenic MMP-3 substrate.

Specifications

Packaging
Kits components
  • Component A: MMP-3 substrate: 270 µL Component B: EDANS, fluorescence reference standard Ex/Em=340 nm/490 nm: 1 mM, 10 µL Component C: APMA, 4-aminophenylmercuric acetate: 1 M, 100 µL Component D: Assay buffer: 60 mL Component E: Stop solution: 30 mL
Chemistry
UniProt number
  • P08254
Properties
Absorbance (nm)
  • 340
Emission (nm)
  • 490
Storage & stability
Storage Conditions
  • Store all components at -20°C. Protect Components A and B from light. Components D and E can be stored at 4°C for convenience.
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Codes
Code Nacres
  • NA.32

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Citations

Association of Matrix metalloproteinase-3 with cardiogenic activity during Noggin-induced differentiation of mouse embryonic stem cells

Int J Cardiol. . 2009 Jan 12 ; 141(1) 49 | DOI : 10.1016/j.ijcard.2008.11.156

  • S. Hong
  • et al