Peptides

VEGFR2/KDR Antagonist - 1 mg

117,00
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  • Cat.Number : AS-60628
  • Availability :
    In stock

Quantity

This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.

Specifications

Chemistry
Sequence one letter code
  • ATWLPPR
Sequence three letter code
  • H-Ala-Thr-Trp-Leu-Pro-Pro-Arg-OH
Molecular Formula
  • C40H61N11O9
Molecular Mass/ Weight
  • 840
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Hyperoxia causes regression of vitreous neovascularization by downregulating VEGF/VEGFR2 pathway.

Invest Ophthalmol Vis Sci . 2013 Feb 18 ; 54(2) 918 | DOI : 10.1167/iovs.12-11291.

  • H. Liu
  • et al

Selective photodynamic therapy by targeted Verteporfin delivery to experimental choroidal neovascularization mediated by a homing peptide to vascular endothelial growth factor receptor-2

Arch Ophthalmol. . 2004 Jul 01 ; 122(7) 1002 | DOI : 10.1001/archopht.122.7.1002

  • RZ. Renno
  • et al