Peptides

Amylin (22-27) [NMeG24, NMeI26], human (IAPP) - 1 mg

219.00
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  • Cat.Number : AS-61937
  • Availability :
    In stock

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Quantity

This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.

Specifications

Chemistry
Sequence one letter code
  • NF-(NMe-G)-A-(NMe-I)-L
Sequence three letter code
  • H-Asn-Phe-(NMe-Gly)-Ala-(NMe-Ile)-Leu-OH
Molecular Mass/ Weight
  • 661.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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