Bacterial Sortase Substrate II , Dabcyl/Edans - 1 mg

Check your price
  • Cat.Number : AS-62230
  • Availability :
    In stock

Alternative choices


This peptide is a C-terminal surface sorting signal with a conserved LPXTG motif, labeled with the Dabcyl/Edans FRET pair. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Surface proteins of Staphylococcus aureus are anchored to the bacterial cell wall by a mechanism requiring this C-terminal sorting signal. Cell wall sorting is the covalent attachment of surface proteins to the peptidoglycan via a C-terminal sorting signal that contains a consensus LPXTG sequence. Cleavage of this FRET substrate by sortase reveals the fluorescent signal that may be measured to study sortase activity. Inhibition of the sortase activity is a potential way of treatment of the staphylococcal infection. The LPXTG motif is conserved in more than 100 surface proteins of Gram-positive pathogens.


Sequence one letter code
  • Dabcyl-QALPETGEE-Edans
Sequence three letter code
  • Dabcyl-Gln-Ala-Leu-Pro-Glu-Thr-Gly-Glu-Glu-Edans
Molecular Mass/ Weight
  • 1472.7
Absorbance (nm)
  • 340
Emission (nm)
  • 490
Conjugation type
  • Double dyes
Modification Name
  • Conjugated
Quantity & Purity
Storage & stability
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
  • Research use
Source / Species
  • bacteria
Code Nacres
  • NA.26

You may also be interested in the following product(s)

Tube of Bacterial Sortase Substrate I peptide, FRET

Bacterial Sortase Substrate I, FRET - 1 mg

Cat.Number : AS-62231
290.00 Excl. Tax
Image of a kit SensoLyte 520 Sortase A Activity Assay Kit Fluorimetric

SensoLyte® 520 Sortase A Activity Assay Kit Fluorimetric - 1 kit

Cat.Number : AS-72228
607.00 Excl. Tax
Vial of Sortase A protease, recombinant protein

Sortase A protease, recombinant - 10 µg

Cat.Number : AS-72229
454.00 Excl. Tax