Peptides

Bid BH3 (80-99) - 1 mg

112,00
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  • Cat.Number : AS-61711
  • Availability :
    In stock

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Quantity

BID is a pro-apoptotic member of the 'BH3-only' (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax.

Specifications

Chemistry
Sequence one letter code
  • EDIIRNIARHLAQVGDSMDR
Sequence three letter code
  • H-Glu-Asp-Ile-Ile-Arg-Asn-Ile-Ala-Arg-His-Leu-Ala-Gln-Val-Gly-Asp-Ser-Met-Asp-Arg-OH
Molecular Formula
  • C95H161N33O32S1
Molecular Mass/ Weight
  • 2309.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins.

PNAS . 2008 Dec 23 ; 105(51) 20327 | DOI : 10.1073/pnas.0808036105

  • J. Chipuk
  • et al

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c.

Nature Cell Biol. . 2008 Nov 23 ; 10(12) 1477 | DOI : 10.1038/ncb1807

  • AE. Vaugh
  • et al