Peptides

Fibrinolysis Inhibiting Factor - 5 mg

99.00
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  • Cat.Number : AS-24262
  • Availability :
    In stock

Quantity

This peptide mimics the N terminus of the alpha-chain of fibrin. It binds to the 'a' polymerization pocket in the alpha-chain more tightly than a peptide corresponding to the chain native sequence GPRV. The complex between GPRP and fibrinogen causes an increased resistance to degradation by plasmin, and the polymerization reaction is depressed by the addition of excess peptide. Fibrin assembly, as well as the acceleration of the factor XIIIa reaction, can be prevented by this homologue of the natural sequence of amino acids.

Specifications

Chemistry
Sequence one letter code
  • GPRP
Sequence three letter code
  • H-Gly-Pro-Arg-Pro-OH
CAS registry number
  • 67869-62-9
Molecular Formula
  • C18H31N7O5
Molecular Mass/ Weight
  • 425.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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Citations

Biocompatibility Assessment of the First Generation PediaFlow Pediatric Ventricular Assist Device.

Artificial Organs . 2012 Jan 01 ; 35(1) 9 | DOI : doi:10.1111/j.1525-1594.2010.01023.x.

  • C. Johnson
  • et al