Antibody

Rabbit anti-Llama VHH, pAb, HiLyte™ Fluor 488 labeled - 100 µg

398,00
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  • Cat.Number : EG-VHH001-HF488
  • Availability :
    In stock
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Quantity

This secondary antibody is broad VHH-specific. It allows detecting VHH's from multiple germline sequence families. It is conjugated to HiLyte™ Fluor 488, a green fluorophore with brighter fluorescence and better photostability than fluoresceins such as FITC. The fluorescence of HiLyte™ Fluor 488 can be observed at excitation/emission wavelength of 499 nm/523 nm. The degree of substitution (DOS) of this antibody conjugate is batch dependent and reported on the certificate of analysis.

Besides the conventional IgGs (IgG1, composed of heavy and light chains), llamas and other camelids produce single chain IgGs (IgG2 and IgG3). They are composed of heavy chains only and are lacking the light chains and the CH1 domains. The antigen binding domain of IgG2 and IgG3, called VHH, is the smallest naturally occurring antibody binding domain. VHHs have amino acid sequences which are highly variable. They belong to 5 germline sequence families, and multiple mutations are observed. This anti-VHH rabbit secondary antibody recognizes VHHs from multiple framework sequence families.

Specifications

Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Concentration
  • 0.5 mg/ml
Purification Method
  • Purified
Storage & stability
Form
  • In solution
Storage Buffer
  • 10 mM phosphate, 150 mM NaCl, pH 7.3 + 1% BSA, 0.05 % NaN3
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Specificity
  • VHHs from llamas and other camelidaes
Clonality
Usage
  • Research use
Source
Host

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