Peptides

Renin FRET Substrate, R-E(EDANS)--K(Dabcyl) - 1 mg

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  • Cat.Number : AS-62022
  • Availability :
    In stock

Quantity

This peptide is a renin substrate (angiotensinogen) labeled with EDANS/ DABCYL FRET pair for renin activity studies. The renin-angiotensin system (RAS), acting through type 1 angiotensin (AT1) receptors, is a master regulator of fluid homeostasis.

Specifications

Chemistry
Sequence one letter code
  • R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
Sequence three letter code
  • H-Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg-OH
CAS registry number
  • 791068-69-4
Molecular Formula
  • C109H157N31O22S2
Molecular Mass/ Weight
  • 2282.8
Properties
Absorbance (nm)
  • 340
Emission (nm)
  • 490
Modification
Conjugation type
  • Double dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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Citations

Increased renal renin content in mice lacking the Na+:H+ exchanger NHE2

Am J Physiol Renal Physiol. . 2008 Feb 20 ; 294(4) F937 | DOI : 10.1152/ajprenal.00591.2007

  • F. Hanner
  • et al

Imaging Renin Content and Release in the Living Kidney

Nephron Physiol. . 2006 Mar 10 ; 103(2) p71 | DOI : 10.1159/000090622

  • I. Toma
  • et al