SensoLyte® AFC Caspase Profiling Kit Fluorimetric - 1 kit

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  • Cat.Number : AS-71116
  • Availability :
    In stock
  • Shipping conditions : Ice delivery fees must be applied

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Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AFC-based substrates yield blue fluorescence upon protease cleavage. They are widely used to monitor caspase activity.
The SensoLyte® Caspase Profiling Kit contains a series of AFC-based peptide substrates (Ex/Em=380 nm/500 nm) as fluorogenic indicators for assaying caspase protease activities. The kit contains a well-designed plate in which a series of AFC-based caspase substrates are coated with both positive and negative controls. It provides the best solution for profiling caspases or caspase inhibitors.


Kits components
  • Component A: Caspase microplate: pre-coated with 8 different caspase substrates Ex/Em=380 nm/500 nm upon cleavage: 2 96-well plates (8 x 12 strips) Component B: AFC, fluorescence reference standard Ex/Em=380 nm/500 nm: 10 mM, 20 µL Component C: Assay buffer: 40 mL Component D: DTT: 1 M, 1 mL Component E: 10X Lysis Buffer: 20 mL
Absorbance (nm)
  • 380
Emission (nm)
  • 500
Storage & stability
Storage Conditions
  • Store components A, B, and D at -20°C. Components C and E can be stored at 4°C for convenience. Component A and B protect from light and moisture.
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
  • Research use
Code Nacres
  • NA.32

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