SensoLyte® AFC Caspase Substrate Sampler Kit Fluorimetric - 1 kit

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  • Cat.Number : AS-71117
  • Availability :
    In production
  • Shipping conditions : Ice delivery fees must be applied

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Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AFC-based substrates yield blue fluorescence upon protease cleavage (Ex/Em=380 nm/500 nm). They are widely used to monitor caspase activity.
The SensoLyte® Caspase Substrate Kit contains a series of AFC-based peptide substrates as fluorogenic indicators for assaying caspase protease activities. It provides the best solution for identifying a suitable substrate for designing AFC-based caspase assays. All the components in the kit are available in bulk package.


Kits components
  • Component A: Caspase substrates Peptide sequence; Ex/Em=380 nm/500 nm upon cleavage: 8 substrates 10 mM, 70 µL Component B: AFC, fluorescence reference standard Ex/Em=380 nm/500 nm: 10 mM, 20 µL Component C: Assay buffer: 80 mL Component D: DTT: 1 M, 1 mL X 2 vials Component E: 10X Lysis Buffer: 20 mL
Absorbance (nm)
  • 380
Emission (nm)
  • 500
Storage & stability
Storage Conditions
  • Store components A, B, and D at -20°C. Components C and E can be stored at 4°C for convenience. Component A and B protect from light and moisture.
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
  • Research use
Code Nacres
  • NA.32

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