Peptides

Endothelin 3, human, rat, mouse, rabbit

197.00
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  • Cat.Number : AS-24323
  • Availability :
    In production

Size

Quantity

Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. This 21 residue peptide (ET-3) is a member of a family of potent vasoconstrictors namely, Endothelin and Sarafotoxin. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. ET-3 is a less potent vasoconstrictor than ET-1 also varying by 6 amino acids in sequence homology.

Specifications

Chemistry
Sequence one letter code
  • CTCFTYKDKECVYYCHLDIIW (Disulfide bridge: 1-15 and 3-11)
Sequence three letter code
  • H-Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bridge: 1-15 and 3-11)
CAS registry number
  • 117399-93-6
Molecular Formula
  • C121H168N26O33S4
Molecular Mass/ Weight
  • 2643.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, porcine, bovine, mouse, rat
Codes
Code Nacres
  • NA.26

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