PNA vs DNA backbone
The backbone of PNAs (Peptide Nucleic Acid) is made of repeating N-(2-aminoethyl)-glycine units linked by peptide bonds. Despite this radical structural change, PNAs are capable of sequence-specific binding in a helix form to its complementary DNA or RNA sequence. Due to its superior binding affinity and chemical/biological stability, PNA has been widely applied in the field of biology.
PNA FISH Probe Details
|C-rich Telomere Probes||5 nmol||repeats of CCCTAA||For both human and mouse|
|G-rich Telomere Probes||5 nmol||repeats of TTAGGG||For both human and mouse|
|Centromere Probes||5 nmol||AAACTAGACAGAAGCATT||For both human and mouse|
|Centromere Protein B Probes||5 nmol||ATTCGTTGGAAACGGGA||Human specific|